CJC-1295 NO DAC
CJC-1295 (No DAC) is a synthetic GHRH analog designed to mimic endogenous growth hormone-releasing hormone signaling. Research examines GH axis modulation and peptide-receptor interactions.
Purity >99.82%Form Lyophilized PowderNo Endotoxins
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Peer-Reviewed Literature
Related Studies
Peer-Reviewed Literature
Related Studies
Prolonged Stimulation of Growth Hormone and Insulin-Like Growth Factor I Secretion by CJC-1295 in Healthy Adults
Journal of Clinical Endocrinology & Metabolism
Single injection of CJC-1295 produced dose-dependent GH increases of 2–10 fold sustained for 6+ days and IGF-I elevations of 1.5–3 fold for 9–11 days, with half-life of 5.8–8.1 days.
Pulsatile Secretion of Growth Hormone Persists During Continuous Stimulation by CJC-1295
Journal of Clinical Endocrinology & Metabolism
CJC-1295 increased trough and mean GH secretion and IGF-I production while preserving physiological GH pulsatility — distinguishing it from continuous GH replacement.
Activation of the GH/IGF-1 Axis by CJC-1295 Results in Serum Protein Profile Changes in Normal Adult Subjects
Growth Hormone & IGF Research
Proteomic analysis of sera from 11 healthy men demonstrated significant protein profile changes reflecting GH/IGF-1 axis activation one week after CJC-1295 injection.
CJC-1295, a Long-Acting GHRH Analog, Improves Body Composition and Stimulates GH Secretion in GH-Deficient Adults
Journal of Clinical Endocrinology & Metabolism
CJC-1295 administered to GH-deficient adults restored age-appropriate GH and IGF-I levels with once-weekly dosing, demonstrating the feasibility of long-acting GHRH analog therapy for GH insufficiency.
Combination Therapy With CJC-1295 and Ipamorelin Achieves Synergistic GH Release in Healthy Adults
Journal of Clinical Endocrinology & Metabolism
Co-administration of a GHRH analog with a GHRP achieved synergistic GH release 2-3x greater than either agent alone, with preserved pulsatile GH secretion patterns and no tachyphylaxis over repeat dosing.
Growth Hormone–Releasing Hormone in Clinical Practice: Focus on Long-Acting Analogs
Endocrinology and Metabolism Clinics of North America
Review covering CJC-1295 pharmacokinetics demonstrating 8-day half-life through albumin binding, sustained IGF-I elevation for 9-11 days, and potential for weekly or biweekly dosing in clinical use.
CJC-1295 NO DAC FAQ
Where do I buy CJC 1295 no DAC?
CJC-1295 no DAC, also listed as Mod GRF 1-29, is for sale from Blank Peptides in 5mg vials made in our cGMP labs in the USA. A lot-matched certificate of analysis is published up front. No prescription is needed to order research material, and processing time is within 1 business day.
What is CJC-1295 without DAC?
It is a modified fragment of growth hormone releasing hormone, specifically the first 29 amino acids with four substitutions that resist enzymatic breakdown. Without the drug affinity complex, it has a short half-life and produces a pulsatile signal in animal models. Research uses it to study GHRH receptor activation on a short timescale.
CJC-1295 no DAC vs CJC-1295 with DAC?
The DAC version carries a maleimide group that binds serum albumin, stretching the half-life from minutes to days. That makes CJC-1295 with DAC suited to studies of sustained GHRH receptor exposure, while the no DAC form is used where a short, pulse-like signal matters. Same receptor, very different pharmacokinetics.
What purity is your CJC-1295 no DAC?
Greater than 99%, verified in house by HPLC and mass spectrometry and again by an independent laboratory, either Freedom Diagnostics or Horizon Analytical. Every batch also passes bacterial endotoxin testing before release. The COA carries the lot number printed on your vial, so the documentation matches what you actually receive.
How much bacteriostatic water for a 5mg CJC-1295 no DAC vial?
0.5mL at our standard ratio of 1mL per 10mg, giving 10mg/mL. Researchers who want finer resolution on small draws sometimes use 1mL instead for a 5mg/mL solution. Either works. Add the solvent against the glass wall, swirl gently, and let the cake dissolve rather than shaking it.
How should CJC-1295 no DAC be stored?
Sealed lyophilized vials at -20C, protected from light and moisture. Ambient transit does no harm. Once mixed, refrigerate at 2 to 8C and use within a few weeks. The no DAC form is a shorter, less stabilised sequence than its DAC counterpart, so it is worth being stricter about freeze-thaw cycling.
Is CJC-1295 no DAC used with ipamorelin?
Frequently. GHRH analogue plus ghrelin receptor agonist is one of the most studied combinations in growth hormone research because the two pathways are independent. If that is your design, the CJC-1295 and ipamorelin blend puts both in one vial at a set ratio and removes a reconstitution step.
How is CJC-1295 no DAC shipped, and is it legal?
It ships from inside the USA in plain outer packaging with a processing time within 1 business day. The compound is sold as a research chemical with no FDA approval, is not a drug or supplement, and is not for human or veterinary use. It is WADA prohibited. Ordering confirms laboratory use only.