(2-Pack) NAD+ – 500mg
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For research use only — not for human consumption, therapeutic, or diagnostic use. By adding to cart you acknowledge these terms.
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About This Compound
Deep technical insights for clinical research
Primary Research Applications
This compound is supplied strictly for in-vitro and preclinical research use only. Research focuses on the modulation of cellular repair mechanisms and upregulation of specific growth factor receptors in laboratory models.
Evaluation of metabolic activity and proliferation rates in relevant cell lineages.
Investigation of intracellular signaling cascades in controlled laboratory settings.
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Pairs & Supplies
The compounds and tools researchers stack with (2-Pack) NAD+ - 500mg.
Peer-Reviewed Literature
Related Studies
NAD+ Metabolism and Its Roles in Cellular Processes During Ageing
Nature Reviews Molecular Cell Biology
Seminal review examining NAD+ as a central redox cofactor in 500+ enzymatic reactions, detailing how age-related NAD+ decline drives senescence, genomic instability, and metabolic dysfunction.
NAD+ Metabolism in Cardiac Health, Aging, and Disease
Circulation
NAD+ pools decline with aging, obesity, and hypertension. Experimental NAD+ elevation improves multiple cardiomyopathies and extends healthspan in preclinical models.
NR-SAFE: A Randomized, Double-Blind Safety Trial of High Dose Nicotinamide Riboside in Parkinson's Disease
Nature Communications
High-dose nicotinamide riboside (3,000 mg daily) was safe and well-tolerated, producing up to 5-fold blood NAD+ increases with improvement in motor scores correlating with NAD+ response.
Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death
Stroke
NAD+ supplementation conferred robust neuroprotection against oxygen-glucose deprivation-induced cell death through enhanced DNA repair capacity and reduced cytotoxic DNA lesions.
Chronic Nicotinamide Riboside Supplementation Is Well-Tolerated and Elevates NAD+ in Healthy Middle-Aged and Older Adults
Nature Communications
First-in-human crossover study demonstrated that 6-week NR supplementation raised whole-blood NAD+ by 60%, was well-tolerated, and showed trends toward reduced arterial stiffness and lowered systolic blood pressure.
NAD+ Repletion Rescues Female Fertility During Reproductive Aging
Cell Reports
NAD+ precursor treatment in aged mice restored oocyte quality, improved ovulation rates, and rescued fertility to levels comparable to young controls — implicating NAD+ decline in age-related infertility.