(2-Pack) Retatrutide – 20mg
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For research use only — not for human consumption, therapeutic, or diagnostic use. By adding to cart you acknowledge these terms.
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About This Compound
Deep technical insights for clinical research
Primary Research Applications
This compound is supplied strictly for in-vitro and preclinical research use only. Research focuses on the modulation of cellular repair mechanisms and upregulation of specific growth factor receptors in laboratory models.
Evaluation of metabolic activity and proliferation rates in relevant cell lineages.
Investigation of intracellular signaling cascades in controlled laboratory settings.
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Pairs & Supplies
The compounds and tools researchers stack with (2-Pack) Retatrutide - 20mg.
Peer-Reviewed Literature
Related Studies
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine
Landmark Phase 2 trial demonstrated retatrutide 12 mg achieved 24.2% mean weight loss after 48 weeks — significantly outperforming all existing single and dual agonist therapies.
Retatrutide, a GIP, GLP-1 and Glucagon Receptor Agonist, for People With Type 2 Diabetes: A Phase 2 Trial
The Lancet
Phase 2 trial showed retatrutide achieved 16.9% weight loss with HbA1c improvements of 2.2%, with 82% of participants reaching HbA1c ≤6.5% after 36 weeks.
Triple Hormone Receptor Agonist Retatrutide for Metabolic Dysfunction-Associated Steatotic Liver Disease
Nature Medicine
Phase 2a trial demonstrated retatrutide 12 mg achieved 82.4% mean reduction in liver fat at 24 weeks, with 86% of participants normalizing liver fat levels below 5%.
Retatrutide, a GIP, GLP-1 and Glucagon Receptor Agonist, for People with Type 2 Diabetes: A Randomised, Double-Blind, Placebo and Active-Comparator Controlled, Parallel-Group, Phase 2 Trial
The Lancet
281 T2D patients receiving retatrutide at highest dose achieved HbA1c reduction of 2.02% vs 0.01% placebo, with 100% of patients reaching target HbA1c <7% at 24 weeks.
Retatrutide Phase 2 Obesity Trial: Efficacy and Safety at 48 Weeks
New England Journal of Medicine
Phase 2 trial in 338 adults with obesity showed retatrutide 12 mg produced 24.2% body weight loss at 48 weeks — the highest reported for any anti-obesity pharmacotherapy — with manageable GI side effects.
Glucagon-Based Multi-Agonist Approaches for Metabolic Diseases
Molecular Metabolism
Preclinical characterization of LY3437943 (retatrutide) showing tri-agonism at GIP/GLP-1/glucagon receptors produced superior weight loss, improved hepatic steatosis, and enhanced energy expenditure versus dual agonists.