SERMORELIN Sermorelin Research Peptide · GHRH Analog · 10mg
Sermorelin is a synthetic 29-amino-acid analog of growth hormone-releasing hormone (GHRH 1-29). Studies address GH axis stimulation, neuroendocrine signaling, and age-related hormone decline.
Purity >99%Form Lyophilized PowderNo Endotoxins
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Related Products
Peer-Reviewed Literature
Related Studies
Peer-Reviewed Literature
Related Studies
Endocrine and Metabolic Effects of Long-Term Administration of Growth Hormone-Releasing Hormone-(1-29)-NH2 in Age-Advanced Men and Women
Journal of Clinical Endocrinology & Metabolism
5-month trial demonstrated significant increases in skin thickness and lean body mass in males receiving nightly subcutaneous sermorelin injections with improved wellbeing markers.
Sermorelin: A Better Approach to Management of Adult-Onset Growth Hormone Insufficiency?
Clinical Interventions in Aging
Comprehensive analysis proposing sermorelin as preferable to recombinant GH for growth hormone replacement, highlighting its advantage of maintaining physiological GH pulsatility.
Beyond the Androgen Receptor: The Role of Growth Hormone Secretagogues in the Modern Management of Body Composition
Translational Andrology and Urology
Review documenting GHS effects on lean mass, adiposity reduction, and potential adjunctive therapy for hypogonadism with comparable fat loss to recombinant GH therapy.
A Two-Year, Open-Label, Multi-Center Study to Evaluate the Safety and Efficacy of Sermorelin (Geref Diagnostic)
Growth Hormone & IGF Research
Two-year open-label study in GH-deficient children demonstrated sermorelin maintained sustained increases in growth velocity, height SDS, and IGF-I without clinically significant adverse events or antibody development.
The Effect of GHRH Analog on Body Composition and Metabolic Parameters in HIV Lipodystrophy
Clinical Endocrinology
GHRH analog therapy reduced trunk fat by 6.2%, increased lean body mass by 1.3 kg, and improved lipid profiles in HIV patients with lipodystrophy over 12 weeks versus placebo.
Growth Hormone Releasing Hormone (GHRH) Neurons and GHRH-Neuron Subtypes in the Hypothalamus
Frontiers in Neuroendocrinology
Comprehensive mapping of GHRH neuronal circuits in the hypothalamus explaining why GHRH analogs like sermorelin preserve physiological pulsatility while exogenous GH replacement suppresses it.
SERMORELIN FAQ
Where can I buy sermorelin online?
Sermorelin is for sale from Blank Peptides in 10mg vials, singly or in 2-packs and 4-packs, produced in our cGMP labs in the USA. Each vial ships with a certificate of analysis matched to its lot number, viewable before you order. No prescription is required for research material, and processing time is within 1 business day.
What is sermorelin?
Sermorelin is the first 29 amino acids of human growth hormone releasing hormone, the shortest fragment that retains full activity at the GHRH receptor. It has been studied since the 1980s, which gives it an unusually deep literature for a research peptide. Work has covered pituitary somatotroph response and endocrine axis modelling in animals.
Is your sermorelin third-party tested?
Yes. Purity is greater than 99%, established by our own HPLC and mass spectrometry and confirmed independently at Freedom Diagnostics or Horizon Analytical, with bacterial endotoxin testing performed on each batch. The COA we publish is specific to your lot, so you can verify the material rather than trust a generic figure.
How do I reconstitute sermorelin?
1mL of bacteriostatic water per 10mg is the standard across our catalogue, capped at 3mL. So 1mL into the 10mg sermorelin vial, landing at 10mg/mL. Run the solvent down the glass wall and swirl gently until the cake has fully dissolved.
How should sermorelin be stored?
Lyophilized vials at -20C, sealed, dark and dry. Freeze-dried peptide tolerates ambient transit temperatures. After reconstitution, keep the vial at 2 to 8C and use within a few weeks. Sermorelin in solution is on the less stable end of the GHRH family, so a short working window matters more here than with some compounds.
Sermorelin vs tesamorelin: what is the difference?
Both are GHRH analogues, but tesamorelin carries a trans-3-hexenoyl group at the N-terminus that resists enzymatic degradation, giving it a longer working half-life. Sermorelin is the unmodified 1-29 fragment. Researchers pick between them based on whether the design calls for a short native-like signal or a stabilised one.
How quickly does sermorelin ship?
Processing time is within 1 business day, then normal domestic transit from inside the USA. Outer packaging carries no compound names. Tracking is emailed when the label prints, and multi-vial packs ship together in one box. Damaged glass is replaced once support has photos.
Is sermorelin sold for human use?
No. This material is a research chemical for laboratory use only, with no FDA approval in this form, and it is not a drug, supplement or veterinary product. It is also WADA prohibited. Ordering confirms you are a qualified researcher and that the compound stays in a laboratory setting.