TB-500 nothing more. nothing less.
TB-500 is a synthetic analog of thymosin beta-4, a naturally occurring 43-amino-acid peptide involved in cell migration and cytoskeletal regulation. Studied in research involving wound healing, inflammatory response, and tissue remodeling.
Purity >99.08%Form Lyophilized PowderNo Endotoxins
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About This Compound
Deep technical insights for clinical research
Primary Research Applications
This compound is supplied strictly for in-vitro and preclinical research use only. Primary applications include the areas below.
Promotes cell migration, angiogenesis, and stem cell mobilization to sites of tissue injury, facilitating accelerated healing responses.
Enhances muscle fiber regeneration, satellite cell proliferation, and reduces fibrotic scarring in skeletal muscle injury models.
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The compounds and tools researchers stack with TB-500.
Peer-Reviewed Literature
Related Studies
Thymosin β4 Activates Integrin-Linked Kinase and Promotes Cardiac Cell Migration, Survival and Cardiac Repair
Nature
Thymosin β4 activated epicardial progenitor cells, inhibited myocardial cell death, stimulated vessel growth, and reduced cardiac scarring through integrin-linked kinase activation.
Thymosin β4 Induces Adult Epicardial Progenitor Mobilization and Neovascularization
Nature
Thymosin β4 activated quiescent epicardial cells, promoting their migration into cardiac tissue where they facilitate coronary neovascularization and regeneration of functional myocardium.
Thymosin Beta 4 Ophthalmic Solution for Dry Eye: A Randomized, Placebo-Controlled, Phase II Clinical Trial
Clinical Ophthalmology
RGN-259 (thymosin β4) showed significant reduction in discomfort scores and improvements in corneal staining in 72 subjects with dry eye disease.
RGN-259 (Thymosin β4) Improves Clinically Important Dry Eye Efficacies in Comparison with Prescription Drugs
Scientific Reports
Thymosin β4 proved equal to or more effective than cyclosporine A, diquafosol, and lifitegrast in promoting mucin recovery, corneal integrity, and reducing inflammation.
Thymosin β4: A Multi-Functional Regenerative Peptide. Basic Properties and Clinical Applications
Expert Opinion on Biological Therapy
Comprehensive review spanning three decades of Tβ4 research documenting its roles in wound healing, anti-inflammation, angiogenesis, and cardiac repair with a focus on translational clinical applications.
Thymosin Beta 4 Promotes Dermal Wound Healing via Its Anti-Inflammatory and Tissue-Regenerative Activities
Journal of Investigative Dermatology
Topical and systemic Tβ4 application accelerated dermal wound healing in aged mice, with enhanced angiogenesis, collagen deposition, and keratinocyte migration compared to controls.
From the Lab
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