MELANOTAN 1 Melanotan I (MT-1) Research Peptide · 10mg
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Melanotan I (afamelanotide) is a linear analog of alpha-melanocyte stimulating hormone. It is studied for MC1R selectivity, eumelanin synthesis, and photoprotection.
Purity >99%Form Lyophilized PowderNo Endotoxins
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Related Products
Peer-Reviewed Literature
Related Studies
Peer-Reviewed Literature
Related Studies
Melanocortin Receptor Agonists, Penile Erection, and Sexual Motivation: Human Studies with Melanotan II
International Journal of Impotence Research
Double-blind crossover study in 20 men found MT-II induced erection in 17/20 subjects without sexual stimulation, with 68% reporting increased sexual desire versus 19% on placebo.
Effect of Melanotan [Nle4, D-Phe7]-α-MSH on Melanin Synthesis in Humans with MC1R Variant Alleles
Peptides
77 Caucasian participants showed significant melanin density increase (p<0.001) versus placebo. Greater effect observed in subjects with MC1R variant alleles compared to wild-type.
An Overview of Benefits and Risks of Chronic Melanocortin-1 Receptor Activation
Journal of the European Academy of Dermatology and Venereology
Comprehensive 2025 review examining melanogenesis mechanisms, safety profile, and clinical utility of melanocortin receptor activation in dermatological research applications.
Subcutaneous Melanotan II for the Treatment of Sexual Dysfunction in Premenopausal Women
Journal of Sexual Medicine
RCT in 18 premenopausal women with female sexual arousal disorder demonstrated Melanotan II significantly increased genital arousal, sexual desire, and sexual satisfaction versus placebo.
Superpotent α-Melanotropin Analogs: Biological Activities and Melanogenesis in Murine Melanoma Cells
Molecular and Cellular Endocrinology
Original characterization of Melanotan II demonstrating 100-1000x greater melanotropic potency than native α-MSH, prolonged biological activity, and high resistance to enzymatic degradation.
Effect of Melanotan-II on Penile Erection in Men with Psychogenic Erectile Dysfunction: Dose-Response
Journal of Urology
Subcutaneous Melanotan II produced clinically meaningful erectile responses in 17 of 20 men with psychogenic ED, with a dose-dependent increase in penile rigidity across multiple monitoring parameters.
Specifications
- Compound
- Melanotan I (afamelanotide), MC1R-selective alpha-MSH analogue
- Form
- Lyophilized powder in a sealed glass vial
- Strength
- 10mg per vial
- Purity
- >99% (brand-wide standard)
- Testing
- HPLC purity, mass spectrometry identity, bacterial endotoxin
- Documentation
- Lot certificate of analysis in the COA library
- Storage
- Lyophilized: sealed at -20°C, protected from light. After reconstitution: 2-8°C, use within 28 days.
- Reconstitution
- Bacteriostatic water, 1-2 mL per vial (bacteriostatic water is sold separately)
- Origin
- Vialed, finished, tested and shipped in the USA
- Shipping
- Processed within 1 business day; cold-chain not required for lyophilized vials
- Intended use
- Research use only. Not for human or veterinary use.
MELANOTAN 1 FAQ
Where is melanotan 1 for sale?
Melanotan 1 is available from Blank Peptides in 10mg vials, made in our cGMP labs in the USA and shipped with a lot-matched certificate of analysis you can read before checkout. Like everything in the catalogue, it is research grade material sold to researchers, so no prescription process applies. Processing time is within 1 business day.
What is melanotan 1?
Melanotan 1, known in the literature as afamelanotide or NDP-alpha-MSH, is a linear tridecapeptide analogue of alpha-melanocyte-stimulating hormone. Norleucine at position four and D-phenylalanine at position seven are the two substitutions that give it far more metabolic stability and far more potency at MC1R than the native hormone. It has a long research record in melanogenesis and in models of light-sensitive skin conditions.
What purity is your melanotan 1, and who tests it?
Greater than 99%. Identity and purity are confirmed by HPLC and mass spectrometry in our lab and then again by an independent run at Freedom Diagnostics or Horizon Analytical, and every batch goes through bacterial endotoxin testing at release. The COA is lot-specific, which matters on a thirteen-residue peptide where a single truncated sequence shows up in the assay.
How do I reconstitute melanotan 1 10mg?
1mL of bacteriostatic water produces a 10mg/mL solution at our standard ratio. Add the water slowly against the glass wall and swirl rather than shake. Keep the reconstituted vial out of direct light, since melanocortin peptides are light-sensitive in solution. Cloudiness that will not clear after a minute of gentle rotation is a reason to contact support instead of proceeding.
How should melanotan 1 be stored?
Sealed and lyophilized at -20C, desiccated and protected from light. Freeze-dried peptide survives ambient transit fine. After reconstitution keep it at 2 to 8C, still shielded from light, and use it within a few weeks. Aliquot before freezing if the protocol runs past that, because repeated freeze-thaw cycles cost you more than storage time does.
What is the difference between melanotan 1 and melanotan 2?
Structure and selectivity. Melanotan 1 is linear and highly selective for MC1R. Melanotan II is a smaller cyclic heptapeptide closed by a lactam bridge, and it hits MC1R, MC3R, MC4R and MC5R without much preference. That difference decides which one a study uses: pigmentation work that needs a clean MC1R readout reaches for melanotan 1, because MC3R and MC4R activity would muddy the result.
How is melanotan 1 shipped?
From inside the USA, processed within 1 business day, in plain outer packaging carrying no compound names. Tracking is emailed at label creation and vials travel padded against impact. Damaged glass on arrival is replaced once support has photos of the box and the vial.
Is melanotan 1 legal to purchase?
It is sold in the United States as a research chemical for laboratory use only. Melanotan 1 holds no FDA approval in this form, it is not a drug, supplement or cosmetic, and it is not intended for human or veterinary use. Ordering confirms you are a qualified researcher and that the material stays in a research setting.
