MELANOTAN 2 Melanotan II (MT-2) Research Peptide · 10mg
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Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH). It is studied for melanocortin receptor binding, pigmentation, and neuroendocrine signaling.
Purity >99%Form Lyophilized PowderNo Endotoxins
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Peer-Reviewed Literature
Related Studies
Peer-Reviewed Literature
Related Studies
Melanocortin Receptor Agonists, Penile Erection, and Sexual Motivation: Human Studies with Melanotan II
International Journal of Impotence Research
Double-blind crossover study in 20 men found MT-II induced erection in 17/20 subjects without sexual stimulation, with 68% reporting increased sexual desire versus 19% on placebo.
Effect of Melanotan [Nle4, D-Phe7]-α-MSH on Melanin Synthesis in Humans with MC1R Variant Alleles
Peptides
77 Caucasian participants showed significant melanin density increase (p<0.001) versus placebo. Greater effect observed in subjects with MC1R variant alleles compared to wild-type.
An Overview of Benefits and Risks of Chronic Melanocortin-1 Receptor Activation
Journal of the European Academy of Dermatology and Venereology
Comprehensive 2025 review examining melanogenesis mechanisms, safety profile, and clinical utility of melanocortin receptor activation in dermatological research applications.
Subcutaneous Melanotan II for the Treatment of Sexual Dysfunction in Premenopausal Women
Journal of Sexual Medicine
RCT in 18 premenopausal women with female sexual arousal disorder demonstrated Melanotan II significantly increased genital arousal, sexual desire, and sexual satisfaction versus placebo.
Superpotent α-Melanotropin Analogs: Biological Activities and Melanogenesis in Murine Melanoma Cells
Molecular and Cellular Endocrinology
Original characterization of Melanotan II demonstrating 100-1000x greater melanotropic potency than native α-MSH, prolonged biological activity, and high resistance to enzymatic degradation.
Effect of Melanotan-II on Penile Erection in Men with Psychogenic Erectile Dysfunction: Dose-Response
Journal of Urology
Subcutaneous Melanotan II produced clinically meaningful erectile responses in 17 of 20 men with psychogenic ED, with a dose-dependent increase in penile rigidity across multiple monitoring parameters.
MELANOTAN 2 FAQ
Where can I buy melanotan 2 online?
Melanotan II is for sale from Blank Peptides in 10mg vials, produced in our cGMP labs in the USA. Each vial arrives with a lot-matched certificate of analysis published before checkout. We supply it strictly as a research chemical, with no prescription step, and processing time is within 1 business day.
What is melanotan II?
Melanotan II, or MT-2, is a cyclic lactam analogue of alpha-melanocyte stimulating hormone. It is a non-selective melanocortin receptor agonist, binding MC1R, MC3R, MC4R and MC5R. Research has used it to characterise melanocortin receptor pharmacology and pigmentation pathways in cell culture and animal models.
What purity is your melanotan 2, and who tests it?
Greater than 99%. Our lab runs HPLC and mass spectrometry on every lot, then sends an independent sample to Freedom Diagnostics or Horizon Analytical for confirmation, with bacterial endotoxin testing on the batch. The COA is published against your lot number. Cyclic peptides need careful assay work, so the independent check is not a formality.
How do I reconstitute melanotan 2 10mg?
1mL of bacteriostatic water gives 10mg/mL, our standard ratio. Run the solvent down the inside of the glass and rotate the vial slowly until the cake clears. Melanotan II is a cyclic lactam and can take a little longer to dissolve than a linear peptide, so be patient rather than shaking it.
How should melanotan 2 be stored?
Sealed lyophilized vials at -20C, kept dark and dry. Ambient temperatures during shipping do no harm to freeze-dried powder. Once reconstituted, store at 2 to 8C, protect from light, and use within a few weeks. Repeated freeze-thaw cycling on solution degrades the cyclic structure faster than it does linear sequences.
Melanotan 2 vs PT-141?
Both come from the alpha-MSH family, but their receptor profiles diverge. Melanotan II binds broadly across melanocortin receptors including MC1R, which is why pigmentation research uses it. PT-141 is weighted toward MC3R and MC4R with little MC1R activity. Study design decides which one answers the question.
How is melanotan 2 shipped?
From inside the USA in plain outer packaging with nothing identifying the contents, with a processing time within 1 business day. Tracking is emailed at label creation. Vials ship padded against impact. Cracked glass or a visibly disturbed cake gets replaced once support has photos.
Is melanotan 2 legal, and is it safe to use?
Melanotan II has no FDA approval, is not a drug, cosmetic or supplement, and is not intended for human or veterinary use. Several regulators have issued warnings about unapproved products containing it. We sell it only as a laboratory research chemical, and ordering confirms it will be used in a research setting by a qualified researcher.
