NAD+ nothing more. nothing less.
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential to cellular energy metabolism and redox reactions. Studied in research involving sirtuin activation, mitochondrial function, and DNA repair signaling.
Purity >99.90%Form Lyophilized CompoundNo Endotoxins
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For research use only — not for human consumption, therapeutic, or diagnostic use. By adding to cart you acknowledge these terms.
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About This Compound
Deep technical insights for clinical research
Synthesis & Purity Overview
Form: Lyophilized powder
Storage: −20°C, desiccated
Reconstitution: Sterile water or PBS
Intra-batch variance below 0.15% across HPLC purity analysis and NAD⁺ enzymatic activity measurement.
Zero detection of heavy metals, endotoxins, residual solvents, and microbial contamination.
Chemical Architecture
C₂₁H₂₇N₇O₁₄P₂
663.43 g/mol
53-84-9
N/A (dinucleotide coenzyme)
Primary Research Applications
This compound is supplied strictly for in-vitro and preclinical research use only. Primary applications include the areas below.
Functions as essential cofactor for oxidation-reduction reactions driving ATP generation in mitochondrial respiration and glycolysis.
Restores age-declined NAD⁺ levels to activate sirtuins and PARPs, reversing metabolic decline and supporting DNA repair mechanisms.
Research Community Feedback
"Consistency is paramount in our cellular model testing. Blank's peptides have maintained the tightest purity specs of any RUO vendor we've audited."
Dr. Julian Kessler
Lead Investigator, Biomatrix Labs
"The availability of detailed MS and HPLC data on the product page saved us two days of redundant internal verification. Professional grade synthesis."
Anika S. Singh
Synthetics Quality Control
"Finally, a supplier that doesn't hide behind consumer marketing. Stark, clear, and high-purity. Exactly what a modern lab needs."
Prof. David Emmerich
Applied Peptide Research
Peer-Reviewed Literature
Related Studies
NAD+ Metabolism and Its Roles in Cellular Processes During Ageing
Nature Reviews Molecular Cell Biology
Seminal review examining NAD+ as a central redox cofactor in 500+ enzymatic reactions, detailing how age-related NAD+ decline drives senescence, genomic instability, and metabolic dysfunction.
NAD+ Metabolism in Cardiac Health, Aging, and Disease
Circulation
NAD+ pools decline with aging, obesity, and hypertension. Experimental NAD+ elevation improves multiple cardiomyopathies and extends healthspan in preclinical models.
NR-SAFE: A Randomized, Double-Blind Safety Trial of High Dose Nicotinamide Riboside in Parkinson's Disease
Nature Communications
High-dose nicotinamide riboside (3,000 mg daily) was safe and well-tolerated, producing up to 5-fold blood NAD+ increases with improvement in motor scores correlating with NAD+ response.
Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death
Stroke
NAD+ supplementation conferred robust neuroprotection against oxygen-glucose deprivation-induced cell death through enhanced DNA repair capacity and reduced cytotoxic DNA lesions.
Chronic Nicotinamide Riboside Supplementation Is Well-Tolerated and Elevates NAD+ in Healthy Middle-Aged and Older Adults
Nature Communications
First-in-human crossover study demonstrated that 6-week NR supplementation raised whole-blood NAD+ by 60%, was well-tolerated, and showed trends toward reduced arterial stiffness and lowered systolic blood pressure.
NAD+ Repletion Rescues Female Fertility During Reproductive Aging
Cell Reports
NAD+ precursor treatment in aged mice restored oocyte quality, improved ovulation rates, and rescued fertility to levels comparable to young controls — implicating NAD+ decline in age-related infertility.
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