EPITHALON Epithalon Research Peptide · 10mg
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Epithalon is a synthetic tetrapeptide based on the naturally occurring epithalamin from the pineal gland. The literature describes work on telomerase activation, circadian regulation, and cellular senescence.
Purity >99%Form Lyophilized PowderNo Endotoxins
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Peer-Reviewed Literature
Related Studies
Peer-Reviewed Literature
Related Studies
Epitalon Increases Telomere Length in Human Cell Lines Through Telomerase Upregulation or ALT Activity
Biogerontology
Epitalon induced telomerase activity and extended telomere length across multiple human cell lines, with cells exceeding the Hayflick limit by approximately 10 passages. Animal studies showed 12–13% lifespan increase.
Overview of Epitalon — Highly Bioactive Pineal Tetrapeptide with Promising Properties
International Journal of Molecular Sciences
Comprehensive review detailing 25 years of epitalon research including telomerase activation mechanisms, methylated DNA binding, histone H1 interaction, and epigenetic regulation of gene expression.
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis During Neurogenesis: Possible Epigenetic Mechanism
Journal of Molecular Neuroscience
Epitalon stimulated gene expression and protein synthesis during neurogenesis through epigenetic mechanisms involving methylated DNA binding and histone protein interactions.
Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium
Lung
Epithalon and related peptide bioregulators activated specific gene expression in aging human bronchial epithelial cells, restoring signal transduction and proliferative capacity to levels seen in younger cells.
Peptides, Genome, Epigenetics
Advances in Gerontology
Epitalon and short peptides interact directly with DNA through complementary nucleotide binding, modulating chromatin structure and gene expression — providing an epigenetic mechanism for peptide bioregulation.
Effect of the Pineal Gland Peptide Preparation Epithalamin on the Lifespan and Spontaneous Tumour Incidence in Female SHR Mice
Mechanisms of Ageing and Development
Epithalamin treatment begun in old age increased mean lifespan of female SHR mice by 12.3%, reduced spontaneous tumour incidence, and inhibited tumour growth rate — extending maximum lifespan.
EPITHALON FAQ
Where is epithalon for sale?
Blank Peptides stocks epithalon in 10mg vials, manufactured in our cGMP labs in the USA. A lot-matched certificate of analysis is published before you order. Research material needs no prescription, and processing time is within 1 business day with tracking emailed at label creation.
What is epithalon?
Epithalon is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, developed from a pineal gland extract studied at the St Petersburg Institute of Bioregulation. Research has examined telomerase activity in cultured human cells, melatonin secretion patterns and lifespan endpoints in rodent studies. Most of the long-running work comes from Russian gerontology groups.
What purity is your epithalon, and is there a COA?
Greater than 99%. Every lot goes through HPLC and mass spectrometry in house, followed by independent confirmation at Freedom Diagnostics or Horizon Analytical, plus bacterial endotoxin testing on the batch. The linked certificate carries the lot number on your vial, so you can check the exact material before it ships.
How much bacteriostatic water for epithalon 10mg?
1mL, producing a 10mg/mL solution, in line with our standard ratio of 1mL per 10mg. Add the water gently against the glass wall and swirl. Epithalon is a four-residue peptide and dissolves almost instantly, so a cloudy solution after a minute is a reason to contact support rather than proceed.
How should epithalon be stored?
Lyophilized and sealed at -20C, protected from light and moisture. Freeze-dried powder handles ambient shipping conditions. After reconstitution, keep the vial at 2 to 8C and use the solution within a few weeks. Short peptides are less forgiving of repeated freeze-thaw cycles than longer sequences, so aliquot for extended protocols.
Epithalon vs DSIP for longevity and circadian research?
Epithalon research approaches circadian and ageing questions through pineal function, melatonin regulation and telomerase activity. DSIP research targets sleep architecture and delta wave activity directly. They overlap only at the edges, and studies using both are usually testing whether those edges connect.
How fast does epithalon ship?
Processing time is within 1 business day, then normal domestic transit from inside the USA. The outer packaging is plain with no compound names on it. Tracking arrives by email when the label prints, and multi-vial packs ship together rather than separately.
Can epithalon be purchased without a prescription?
Yes, because it is a research chemical rather than a medicine. Epithalon has no FDA approval, is not a drug or dietary supplement, and is not intended for human or veterinary use. Ordering confirms that you are a qualified researcher and that the compound stays inside a laboratory setting.
